Category: Pharmacology

I have attached the assignment details. 15 marks with 3 parts each worth 5 marks

I have attached the photos with the assignment detail it is 15 marks with 3 tasks 5 marks each

Table of contents

List of figures

List of tables

List of abbreviations

Page numbers based on guideline

Cover paper based on guideline

Assignment – develop a short 15- 20-minute PowerPoint presentation on the following that will include a brief overview of the long-acting injectable (LAI), the doses and schedules and conversion from PO to the LAI used, monitoring parameters, etc. Also, include in your presentation 3 questions that are questions ONLY to dosing considerations (not questions like Do you use gluteal or deltoid muscle for injection as this should be covered in our PowerPoint or patient stopped LAI for 6 months what to do now? how to restart? etc.). Make sure questions are multiple choice only, and you provide a slide with your detailed explanation for each question asked, following that question. Thus, your 3 questions should be a case-specific scenario (e.g. patient has a dose of Zyprexa oral of 30 mg but the zyprexa relpreev is a conversion for a much lower mg/day dose, so how to you dose it? etc. This will require for all of you to look at doing that is OUTSIDE of the dose range that is included in the package insert, etc Be sure to also include how to decrease the oral dose when initiating the LAI (if applicable) and by what % is the decrease, etc.(this is especially true for some of these agents) Please Proof-read your slides for grammar and spell check and make sure all info is accurate and complete (use your knowledge of making slides eg. bullets and not complete sentences, unless warranted, etc) Also if there is common info for your medications then put that info together (ie. minimize the number of slides- e.g. the monitoring, ADRs, etc). ALSO include what to do if patient misses dose (when to restart fully vs. increase dose or other options)

drugs you are assigned: Abilify Maintena, Aristada, Aristat Initio, Abilify Asimtufii (include for Abilify Maintenna what drug interactions would cause 300 mg dose vs.400 mg dose, etc) Invega Sustenna,

Some of the questions are straightforward and some may require you to say, contact the drug company to get an answer (ie. or doses outside the range Please be mindful of including information that a pharmacist would need to know! (do not include the instructions for injection, other than gluteal vs. deltoid, etc

I need 4 separate Cloze deletion Anki created files that includes all the info from files given. 1 file per anki

Please use the attached form to answer the following questions. I have attached two files: the DI form and a DI exampleplease review both to understand the required format and answering style.

For each question, provide three different study/write-up styles.

Questions:

1. What is the appropriate time to stop CPR? Also, what does ROSC mean, and how can it be achieved?
2. Summarize the pharmacokinetics (PK) in Down syndrome in a table format (ADME).
3. What is a Forest Plot? Explain each of its components and their meanings, and when it is used.

What is lipophilicity and why it is important.

Sabas que controlar la presin arterial puede cambiar por completo el destino de un paciente? Los frmacos antihipertensivos no solo reducen cifras en un tensimetro: protegen cerebro, corazn, riones y vasos, y son una de las bases del tratamiento cardiovascular en medicina. Para el estudiante, entenderlos es clave porque cada grupo tiene un mecanismo, una indicacin y un perfil de efectos adversos que se traduce directamente en decisiones clnicas. Aprender antihipertensivos no es memorizar nombres; es comprender cmo una molcula puede prevenir un infarto, un accidente cerebrovascular o una insuficiencia renal.

Parkinsons Disease Drugs Assignment

Introduction:

Parkinsons disease is a progressive neurodegenerative disorder caused by loss of

dopamine-producing neurons in the brain, especially in the substantia nigra. It leads to tremors,

rigidity, bradykinesia, and postural instability.

1. Levodopa + Carbidopa

Mechanism of Action:

Levodopa converts into dopamine in the brain. Carbidopa prevents peripheral breakdown of

levodopa.

Dose & Timing:

100/25 mg, 34 times daily, taken with or after meals.

Side Effects:

Nausea, vomiting, dyskinesia, hallucinations, hypotension.

Contraindications:

Narrow-angle glaucoma, severe psychosis, MAO inhibitors.

2. Dopamine Agonists (Pramipexole, Ropinirole)

Mechanism:

Stimulate dopamine receptors directly.

Dose:

Pramipexole 0.125 mg three times daily (gradual increase).

Side Effects:

Sleepiness, hallucinations, impulse control disorders.

Contraindications:

Psychiatric illness, hypotension.

3. MAO-B Inhibitors (Selegiline, Rasagiline)

Mechanism:

Inhibit dopamine breakdown enzyme MAO-B.

Dose:

Selegiline 5 mg twice daily (morning preferred).

Side Effects:

Insomnia, headache.

Contraindications:

SSRIs (risk of serotonin syndrome).

4. COMT Inhibitors (Entacapone)

i need 4 hours of recordings to be writen into notes