Category: Chemistry

  • Chemistry Question

    My notes will provide you explanation about chemical reaction, change occur during chemical reaction,chemical equation, chemical equation, balance chemical equation balance chemical equation, writing a chemical equation, some chemical formula, and example of balanced equation

  • Chemistry Question

    I need you to build an academic-style website for my university assignment. I will provide you with:

    1. My written report (PharmaNova document)
    2. My presentation slides ()
    3. A website link/template for editing ()

    The website must look professional, clean, and scientific (like a pharmaceutical company website), not casual or blog-style.

    STRUCTURE (VERY IMPORTANT must follow this exactly):

    The website should have approximately 8 sections/pages:

    1. Home Page
    • Company name: PharmaNova
    • Tagline (e.g. Innovating Targeted Therapies for Intestinal Disease)
    • Brief overview of our drug and purpose
    • Clean hero section with scientific feel
    1. About the Disease & Target
    • Explain diarrhoea (global burden)
    • Explain P2Y14 receptor (GPCR, role in inflammation and necroptosis)
    • Why this target matters
    1. Drug Discovery (Hit Identification)
    • Explain how Hit 1 and Hit 2 were discovered
      (HTS + virtual screening)
    • Brief explanation of assays (radioligand, FLIPR)
    • Show structures (if possible)
    1. Lead Optimisation
    • Show how hits were improved
    • Explain Compound 66 66-M
    • Explain Compound 8 8-MM
    • Focus on WHY changes were made (LogP, metabolism, etc.)
    1. Final Lead Compound
    • Highlight Compound 66-M
    • Why it was selected (potency, PK, permeability)
    • Comparison vs other compound
    1. Tablet Formulation (DETAILED SECTION VERY IMPORTANT)
    • Why tablet formulation was chosen
    • Full breakdown of excipients:
      • Binder
      • Filler
      • Disintegrant
      • Lubricant
      • Coating
    • Explain role of each clearly
    • Must look scientific and detailed
    1. Challenges & Alternative Formulation
    • Challenges (solubility, permeability, stability, etc.)
    • ONE alternative formulation (e.g. capsule or liquid)
    • Pros and cons vs tablet
    1. Sustainability & Future Steps
    • Social responsibility (global diarrhoea burden)
    • Access to medicine
    • Cost considerations
    • Environmental/sustainable manufacturing
    • Next steps (preclinical clinical trials)

    DESIGN REQUIREMENTS (VERY IMPORTANT):

    • The design must look visually attractive and professional (high distinction level)
    • Clean layout with clear sections (not blocks of text)
    • Use a modern pharmaceutical style (white + blue/green color theme)
    • Use headings, spacing, and visual hierarchy properly
    • Include icons, cards, or sections to break content
    • Make it look like a real biotech/pharma company website
    • Ensure it is easy to read and visually engaging

    DIAGRAMS & FIGURES:

    • Review the diagrams and figures in the files I provide
    • Only include diagrams that are clear, labelled, and professional
    • If any diagrams are low quality or unclear, improve or redesign them
    • Chemical structures must be clearly visible and labelled (Figure 1, Figure 2, etc.)
    • Use visuals to support explanation, not just decoration

    CONTENT RULES:

    • DO NOT change scientific meaning
    • Improve readability but keep academic tone
    • Break long text into sections
    • Highlight key points

    EXTRA:

    • Include placeholders for chemical structures if needed
    • Make sure navigation is smooth (menu at top)
    • Each section should feel like its own page

    DEADLINE:
    I need this completed by the 26th.

    I will provide all materials your job is to structure, design, and present it professionally.

    Criteria of grading:

    BRIEF OVERVIEW of new medicine – There is a clear concise and overview, no flaws in logic, demonstrates insight


    BRIEF SUMMARY of disease and target – There is a clear concise and overview, no flaws in logic, demonstrates insight

    BRIEF SUMMARY of hit discovery and optimisation to give lead compound – There is a clear concise and overview, no flaws in logic, demonstrates insight

    DETAILED DESCRIPTION of tablet formulation of your lead compound – There is a clear and detailed description, with STRONG evidence of high-level understanding

    BRIEF DESCRIPTION of one other possible formulation that could be suitable for your lead compound – There is a clear and concise description


    DETAILED DESCRIPTION of sustainability and social responsibility issues that relate to your disease/target/drug, and how you could address them – There is a clear and detailed description, with STRONG evidence of high-level understanding

    BRIEF DESCRIPTION of the next steps for your formulated medicine – There is a clear and concise descrption


    Website structure – Website is straightforward to navigate, intellectually engaging

  • What is a solubility?

    Maximum amount of solute which can be dissolved in a specific amount of solvent at a specific temperature

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    Here all the information & formulas :-


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    How does pH level affect the rate of enzyme-catalyzed reactions in living cells?

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    It is because tthe zinc reacts with hydrochloric acid and single displacement reaction take place in which zinc chloride and hydrogen gas is produced.

  • Task 3: Material balance

    Part A Excel (4 steps):

    Step 1 fixes Task 3.1 the biomass back-calculation with the actual numbers, so you can repair those broken reference cells manually.

    Step 2 gives you the exact mol values for every downstream unit (HTS WGS LTS WGS CO Remover Methanator Dryer Haber-Bosch), with the formula used for each species so you can re-enter or re-link the cells properly rather than just hardcoding.

    Step 3 shows how to scale everything up from the per-100-mol basis to actual plant-scale kgmol/day and kg/day flows.

    Step 4 walks you through setting up Excel Solver correctly the instructor specifically requires this.

    Part B Word (written section):

    Covers exactly what to write for 3.1 and 3.2, the summary table format that fits the 2-page limit, all 8 assumptions you need to explicitly state, and the key equations the instructor expects to see.

    At the end there’s a checklist you can tick off before submission on 22 May. Let me know if you’d like help with any specific step.

    will upload other documents when assigned

    CHECKLIST Before Submission

    Use this to verify Task 3 is fully complete:

    3.1 Biomass daily and annual requirement calculated and shown with sample calculation

    Excel All 9 unit columns filled with species mole flows (no #REF! or blank cells)

    Excel All values scaled up to kgmol/day and kg/day plant-scale flows

    Excel Solver set up, run, and result recorded

    Excel Overall mass balance closes (? in ? out within 1%)

    Word Section 3.1 paragraph written with sample calculation

    Word Section 3.2 summary table included

    Word All 8 assumptions stated with references

    Word Key equations listed

    Word Total Task 3 section 2 A4 pages, Calibri 11

    References All sources cited consistently

  • Task 3: Material balance

    Part A Excel (4 steps):

    Step 1 fixes Task 3.1 the biomass back-calculation with the actual numbers, so you can repair those broken reference cells manually.

    Step 2 gives you the exact mol values for every downstream unit (HTS WGS LTS WGS CO Remover Methanator Dryer Haber-Bosch), with the formula used for each species so you can re-enter or re-link the cells properly rather than just hardcoding.

    Step 3 shows how to scale everything up from the per-100-mol basis to actual plant-scale kgmol/day and kg/day flows.

    Step 4 walks you through setting up Excel Solver correctly the instructor specifically requires this.

    Part B Word (written section):

    Covers exactly what to write for 3.1 and 3.2, the summary table format that fits the 2-page limit, all 8 assumptions you need to explicitly state, and the key equations the instructor expects to see.

    At the end there’s a checklist you can tick off before submission on 22 May. Let me know if you’d like help with any specific step.

    will upload other documents when assigned

  • sell notes

    i will chemistry all notes sell