responses should be a minimum of 250 words, scholarly written, APA formatted, and referenced. A minimum of 2 references are required (one may be the textbook).
EB is a 54-year-old man of European decent with diet controlled diabetes mellitus, HTN, dyslipidemia, and gastroesophageal reflux disease (GERD). He is a current smoker. His current medications include lisinopril 20 mg/day, amlodipine 10 mg/day, pravastatin 40 mg/day, and omeprazole 20 mg/day. Fasting laboratory results show glucose 109 mg/dL, TC 197 mg/dL, LDL-C 128 mg/dL, HDL-C 37 mg/dL, and TG 166 mg/dL. His non-HDL is 160 mg/dL. His systolic blood pressure is 130 mmHg and the PCE (pooled Cohort Equation) estimates his 10 year risk of ASCVD to be 26.8%.
- Risk Assessment & Guidelines Application
- Based on EBs ASCVD risk, how would you classify his 10-year risk, and how does that influence your statin therapy choice?
- What role do his diabetes, hypertension, and smoking status play in decision-making?
- Statin Therapy Selection
- EB is currently on pravastatin 40 mg/day (moderate-intensity). Would you continue, adjust, or switch therapy? Explain your rationale.
- Which statin agents and doses are considered high-intensity, and why are they preferred in this scenario?
- How would you define and monitor treatment success?
- Monitoring and Safety
- How would you counsel EB regarding potential statin-associated muscle symptoms (SAMS)?
- If EB develops SAMS, what are your management options?
- Lifestyle Modifications & Patient Education
- What specific lifestyle interventions would you recommend for EB, and how would you prioritize them?
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