Use at least two of the following databases to search for peer-reviewed literature relevant to your topic:
1- PubMed / MEDLINEScopusWeb of ScienceCochrane LibraryEmbaseGoogle Scholar (supplementary only)
Apply Boolean operators (AND, OR, NOT), MeSH terms where applicable, and date filters to ensure relevance. Prioritise primary research articles, systematic reviews, and meta-analyses published in the last 10 years. Retain a record of your search strategy (databases used, keywords, filters applied)
2-Write Three Paragraphs Under Introduction
Using the literature you have retrieved and critically appraised, write three cohesive paragraphs that together constitute the Introduction section of your research proposal. Each paragraph has a specific rhetorical purpose such as Global Context
Introduce the disease, condition, or phenomenon your study addresses. Establish its global epidemiological burden, clinical significance, and relevance to public health or precision medicine. All factual claims must be supported by in-text citations. Knowledge Gap & Rationale for Your Study
Identify what remains unknown, under-studied, or contested in the existing literature. Use this gap explicitly to justify why your proposed study is necessary, timely, and significant. This paragraph should lead the reader naturally toward your research question
3- Compile a Full Reference List
At the end of your document, provide a complete reference list for all sources cited in-text. Use Vancouver referencing style (numbered, in order of first appearance in text). A minimum of 10 peer-reviewed references is required. All references must be formatted completely and consistently, including author names, article title, journal name, year, volume, issue, and page numbers or DOI.
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